Baked Salmon with Cajun Seasoning

Golden-brown Baked Salmon with Cajun Seasoning flaking perfectly with a fork on a baking sheet. Pin it
Golden-brown Baked Salmon with Cajun Seasoning flaking perfectly with a fork on a baking sheet. | tasteterritory.com

Oven-baked salmon gets a spicy makeover with a homemade Cajun seasoning blend featuring paprika, garlic, onion, and herbs. The fish develops a beautiful crust while staying incredibly moist inside, ready in under 30 minutes.

The smell of paprika and garlic hitting the hot oven air always stops me in my tracks, no matter how busy the evening is. I stumbled upon this method on a frantic Tuesday when takeout felt like too much effort but I still wanted something exciting. It turned a basic piece of fish into the kind of meal that makes you pause between bites. The bold spices wake up your senses faster than a morning cup of coffee.

My usually picky brother actually asked for seconds the last time I served this, which is basically a five star review in my book. We were sitting around the small kitchen island, just talking and laughing while the salmon broiled for that final minute. Seeing everyone go quiet just to enjoy the food was the best part of that night.

Ingredients

  • Salmon fillets: Skin on helps keep the fish moist during the high heat baking.
  • Cajun seasoning: Look for a blend with a bit of kick to really wake up your palate.
  • Paprika: Smoked paprika adds a deep, savory layer that sweet paprika just cannot match.
  • Olive oil: This helps the spices stick to the fish and promotes even browning.
  • Lemon: A squeeze of fresh acidity cuts right through the rich spices.

Instructions

Prep the oven:
Get your oven nice and hot at 400 degrees so the fish sears immediately.
Dry the fish:
Pat the fillets very dry with paper towels to ensure a crispy skin.
Make the rub:
Whisk the spices together in a small bowl until they are fully blended.
Season the fish:
Rub the oil over the salmon and press the spice mix firmly onto the flesh.
Bake:
Place lemon slices on top and bake until the fish flakes apart easily with a fork.
A vibrant, spicy Baked Salmon with Cajun Seasoning garnished with fresh parsley and lemon. Pin it
A vibrant, spicy Baked Salmon with Cajun Seasoning garnished with fresh parsley and lemon. | tasteterritory.com

There is something grounding about eating this with your hands or just a simple fork, letting the flavors linger without needing fancy silverware. It reminds me of summer dinners that stretch late into the evening because nobody wants to leave the table. That simple connection is what cooking is really all about.

Making The Most Of Leftovers

Flake any leftover fish into a salad the next day for a lunch that feels fresh and new. The spices actually mellow out slightly and meld beautifully with a vinaigrette. It is the ultimate zero waste meal for a busy work week.

Managing The Spice Level

I always taste my spice blend before putting it on the meat because some brands are surprisingly hot. If you are sensitive to spice, dial back the cayenne and rely on the garlic and thyme for flavor. You want a tingle on your tongue, not a fire that hides the salmon taste.

Side Dish Ideas

A light side dish balances the bold seasoning of the fish perfectly.

  • Roasted asparagus with lemon zest works wonders here.
  • Cauliflower rice soaks up the extra juices without being heavy.
  • A simple arugula salad adds a peppery crunch to the meal.
Close-up of a tender Baked Salmon with Cajun Seasoning revealing moist, succulent flakes. Pin it
Close-up of a tender Baked Salmon with Cajun Seasoning revealing moist, succulent flakes. | tasteterritory.com

I hope this brings a little spice and joy to your dinner table tonight. Enjoy every delicious bite.

Recipe Q&A

Bake at 400°F (200°C) for 12–15 minutes until the fish flakes easily with a fork and reaches 145°F internal temperature.

Yes, thaw frozen salmon completely in the refrigerator overnight before seasoning and baking for best results.

The heat level is moderate and adjustable. Reduce or omit the cayenne pepper for a milder version everyone will enjoy.

Pair with roasted vegetables, fluffy rice, quinoa, or a crisp green salad for a complete and satisfying meal.

Absolutely—combine paprika, garlic powder, onion powder, thyme, oregano, and cayenne for a fresh, flavorful blend ready in minutes.

Baked Salmon with Cajun Seasoning

Flaky salmon fillets coated in zesty Cajun spices and baked until tender and juicy.

Prep 10m
Cook 15m
Total 25m
Servings 4
Difficulty Easy

Ingredients

Fish

  • 4 (6 oz) salmon fillets, skin-on or skinless

Cajun Seasoning Blend

  • 2 tablespoons Cajun seasoning
  • 1 teaspoon paprika, smoked or sweet
  • 1/2 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • 1/2 teaspoon dried thyme
  • 1/2 teaspoon dried oregano
  • 1/4 teaspoon cayenne pepper

Additional Ingredients

  • 2 tablespoons olive oil
  • 1 lemon, sliced
  • Fresh parsley, chopped
  • Salt and black pepper, to taste

Instructions

1
Preheat and Prepare Baking Sheet: Preheat oven to 400°F. Line a baking sheet with parchment paper or lightly grease with cooking spray.
2
Prepare Salmon Fillets: Pat salmon fillets dry with paper towels to remove excess moisture. Place fillets skin-side down on the prepared baking sheet.
3
Mix Cajun Seasoning: In a small mixing bowl, combine Cajun seasoning, paprika, garlic powder, onion powder, dried thyme, dried oregano, and cayenne pepper. Stir until thoroughly blended.
4
Coat Salmon with Oil: Drizzle olive oil evenly over each salmon fillet. Gently rub the oil into the fish to ensure even coverage.
5
Apply Seasoning: Sprinkle the Cajun seasoning mixture generously over each fillet, pressing gently to adhere. Season with additional salt and black pepper as desired.
6
Add Lemon Slices: Place a lemon slice on top of each seasoned salmon fillet to infuse citrus flavor during baking.
7
Bake to Perfection: Bake for 12–15 minutes until salmon flakes easily with a fork and reaches an internal temperature of 145°F. The fish should appear opaque throughout.
8
Garnish and Serve: Remove from oven and immediately garnish with chopped fresh parsley. Serve hot with your choice of sides.
Additional Information

Equipment Needed

  • Baking sheet
  • Parchment paper or aluminum foil
  • Small mixing bowl
  • Measuring spoons
  • Kitchen knife and cutting board
  • Paper towels
  • Meat thermometer

Nutrition (Per Serving)

Calories 320
Protein 34g
Carbs 2g
Fat 18g

Allergy Information

  • Contains fish (salmon)
  • Store-bought Cajun seasoning may contain mustard or other allergens—verify ingredient labels
Sabrina Lowell